I take it you have gone as evil? Where do you store you stuff with that?
Funny enough I got to evil cause I kept steeling stuff, problem was I had a crap gun so I struggled to get out of megatron alive. Restarted the game from the vault as I wanted to play as neutral.
First playthrough is excellent as a badboy. You gain the mission from that guy who wants you to blow up Megaton and he'll give you a suite in Tenpenny where you can store all your stuff anyway. Blowing it up will result in the lowest Karma in the game but totally worth it when you can loot everything, buy back your Karma at the Church later and get a suite anyway. Or if you're a goody goody like me, you'll save Megaton, get a suite there and be uperpoor.
I finished the game in like 13 hours on my first playthrough, pretty weird since I did do a lot of the sidequests as well. But when I unlocked the Explorer perk, I was kinda like "Holy hell".
Absolutely love the uniqueness of the game. At one stage I managed to get about 7 other allies, making a team of 8 and hunting a breeze!